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ONLINE N&PP Seminar by Michelle Mielke

April 23, 2020 @ 3:00 pm - 4:00 pm

Due to COVID-19, this seminar will be held online through BBCollaborate-Ultra. Access can be found through the following link: https://us.bbcollab.com/guest/4311e6490fff434292066b55f39660f6

Michelle Mielke, PhD, Professor of Epidemiology, Department of Neurology, Mayo Clinic College of Medicine presents: Considering Sex and Gender Differences in, and Sex-Specific Risk Factors for, Alzheimer’s Disease Dementia

With the aging of the population, the burden of Alzheimer’s disease (AD) dementia is rapidly expanding.  Although tremendous strides have been made in AD research over the past several years, limited attention has been given to sex and gender differences in AD. This has led to significant knowledge gaps in research and a lack of awareness among the research community on sex and gender differences in AD. While men may have a higher risk of mild cognitive impairment (MCI), an intermediate stage between normal aging and dementia, women are disproportionally affected with AD.  One explanation is that men may die of competing causes of death earlier in life, so that only the most resilient men may survive to older ages.  However, many other factors should also be considered to explain the sex differences.  This presentation will discuss the differences observed in men versus women in the incidence and prevalence of MCI and AD, in the structure and function of the brain, and in the sex-specific and gender-specific risk and protective factors for AD. Understanding both sex- and gender-specific risk and protective factors for AD is critical for developing individualized care for both the prevention and treatment of AD.



April 23, 2020
3:00 pm - 4:00 pm